Hiring in life sciences? Share your open positions with our professional community. Read more Close

Advertisement

Association Between Adverse Childhood Experiences and Intrinsic Capacity Trajectories Among Older People in China: Evidence From CHARLS.

Created on 18 Jul 2026

Authors

Xinyue Zhang, Wenyang Han, Yiqun Li, Xiaowei Zheng, Yuqing Chen

Published in

International journal of psychiatry in medicine. Pages 912174261469840. Jul 18, 2026. Epub Jul 18, 2026.

Abstract

ObjectiveThis study explored the effects of adverse childhood experiences (ACEs) in older adults on long-term intrinsic capacity (IC) and trajectories of change in IC over 5 years from 2011 to 2015.MethodsA total of 2847 participants aged 60 years and older from the China Health and Retirement Longitudinal Study (CHARLS) were included in analyses. Twelve ACEs were retrospectively assessed by questionnaire in 2014. The number of ACEs was summed and categorized into 5 groups: 0, 1, 2, 3, and 4 or more ACEs. IC was assessed using a measure that examined five domains: locomotor, cognitive, sensory, vitality, and psychological.ResultsOverall, 87.4% of participants reported exposure to at least 1 of the 12 ACEs (Group 2) and 16.6% had experienced 4 or more ACEs (Group 5). Compared to participants without ACEs exposure (Group 1), those experiencing 1, 2, 3 and 4 or more ACEs (Groups 2-5) predicted worse IC (β = 0.085, 95% CI = -0.169 to -0.001, P < 0.05, to β = -0.44, 95 % CI = -0.54 to -0.34, P < 0.001, respectively across the four groups, demonstrating a dose-effect response. Three IC trajectories were identified (low-stable, moderate-stable, and high stable). Individuals with experience 2, 3 and 4 or more ACEs (Groups 3-5) predicted a significantly increased risk of moderate-stable and low-stable IC trajectories. In addition, physical abuse, household mental illness, domestic violence, bullying and parental disability was negatively related to IC and predicted an increased risk of moderate-stable and low-stable trajectory in long-term follow-up.ConclusionExposure to ACEs negatively impacts IC and predicts increased risk of moderate-stable and low-stable IC trajectory (vs. high stable) over time.

PMID:
42470132
Bibliographic data and abstract were imported from PubMed on 18 Jul 2026.

Read full publication at:
Please sign in to see all details.

Advertisement

Stats

  • Community rating n/a 0 votes
  • Reviewers' rating n/a 0 votes
  • Your rating

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

  • Recommendations n/a n/a positive of 0 vote(s)
  • Views 3
  • Comments 0

Recommended by

  • No recommendations yet.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.

Advertisement