Association between platelet-to-hemoglobin ratio and contrast-induced acute kidney injury after percutaneous coronary intervention.

Authors

Qiqiang Li, Leigang Tian, Lijian Li, Yingming Shi, Yujing Li, Linxiao Deng, Yong Liu, Kedong Han

Published in

BMC nephrology. Jul 19, 2026. Epub Jul 19, 2026.

Abstract

In patients suffering from coronary artery disease, the measured platelet-hemoglobin ratio (PHR) is a key biomarker of prognosis. However, the association between PHR and contrast-induced acute kidney injury (CI-AKI) outcomes after percutaneous coronary intervention (PCI) are unclear.
In a retrospective study, 26,479 patients (63.3 ± 11.5 years of age, 22.1% female) who underwent PCI were enrolled. CI-AKI was defined as serum creatinine levels above 0.3 mg/dL, exceeding the baseline by more than 50%, in the first 48 h following contrast exposure. The relationship between PHR and CI-AKI was clarified through univariate and multivariable logistic regression analyses.
In summary, CI-AKI occurred in 1,707 patients (6.4%) following PCI. The association of an increased PHR with elevated CI-AKI incidence was determined via multivariate logistic regression analysis (odds ratio for Q4 vs. Q1, 1.42; 95% confidence interval [95% CI], 1.20-1.68; P < 0.001). Restricted cubic spline analysis indicated a linear PHR-CI-AKI relationship (non-linearity P = 0.060).
A high PHR was strongly correlated with elevated CI-AKI incidence, indicating PHR as a factor independently associated with CI-AKI.

PMID:
42471609
Bibliographic data and abstract were imported from PubMed on 19 Jul 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.