Weight-gain-for-gestational-age z-score in twin pregnancies in China and its association with preterm birth: a retrospective cohort study.

Authors

Ying Hu, Shuqi Zhu, Jia Liu, Die Hong, Hong Wen, Lu Chen, Xixi Chen, Yuqing Zou, Jingjing Liu, Danqing Chen, Lu Qi, Zhaoxia Liang

Published in

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. Volume 46. Issue 1. Pages 2703754. Epub Jul 19, 2026.

Abstract

To evaluate the association between the weight-gain-for-gestational-age z-score and preterm birth (PTB) in a large Chinese twin pregnancy cohort.
A hospital-based retrospective study included 2832 twin pregnancies between January 1, 2015, and December 31, 2019. The primary composite outcome was defined as PTB. The total gestational weight gain was converted into z-score, and logistic regression models were used to examine the associations between z-scores and PTB.
We developed a weight-gain-for-gestational-age z-score to determine the gestational weight gain during twin pregnancies in Chinese women. Low (Our findings indicate that inadequate gestational weight gain, as evaluated by the z-score, is associated with a significantly increased risk for SPTB, whereas inadequate and excessive gestational weight gain are associated with a significantly increased risk for IPTB, in a large Chinese twin pregnancy cohort.

PMID:
42472474
Bibliographic data and abstract were imported from PubMed on 20 Jul 2026.

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