[Incidence and prevalence trends and age-period-cohort of genital prolapse in China from 1990 to 2023].

Authors

J Q Zhang, L Li, Z N Shi, Q Zhang, L Yang, C C Ren

Published in

Zhonghua fu chan ke za zhi. Volume 61. Issue 7. Pages 564-571. Jul 25, 2026.

Abstract

Objective: To analyze the epidemiological characteristics and long-term trends of women's genital prolapse in China. Methods: The data of the incidence and prevelence of genital prolapse in China in Global Burden of Disease 2023 were collected. The time trend analysis was performed using Joinpoint regression model to calculate annual percent change and average annual percent change (AAPC) of standardized incidence and prevalence. The age-period-cohort model was used to investigate the effects of age, period and birth cohort on the disease burden. Results: From 1990 to 2023, the absolute number of incident and prevalent cases of genital prolapse among Chinese women increased significantly (by 111.07% and 126.06%, respectively). However, the age-standardized incidence rates and age-standardized prevalence rates decreased respectively (AAPC=-0.47% and -0.52%, respectively). The age-period-cohort model analysis showed that: (1) the age-effect showed an increasing trend in the risk of genital prolapse incidence and prevalence (all P<0.05), expecially growing rapidly after 40 years old and 80 years old; (2) the period-effect indicated an increasing trend in the risk of genital prolapse incidence and prevalence over time (all P<0.05); (3) the cohort-effect demonstrated that compared to those born in earlier cohorts, women born in more recent cohorts had a significantly lower risk of genital prolapse (all P<0.05). Conclusions: Although the age-standardized incidence rates and age-standardized prevalence rates of genital prolapse among Chinese women have declined, the absolute number of cases and the disease burden continue are increasing. In response to the public health challenges presented by genital prolapse, the women aged 45 and above should be the focus of future genital prolapse prevention and control efforts, strengthened early screening and health management.

PMID:
42477918
Bibliographic data and abstract were imported from PubMed on 21 Jul 2026.

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