Invasive Primary Melanoma of the Kidney: A Rare Presentation of an Uncommon Malignancy and Review of Literature.

Authors

Joshua Ghoulian, Jersey-Kate Castillo, Ronaldo Dario Gnass, Vicente Ramos-Santillan, Antoin Douglawi, David Caba, Muhannad Alsyouf

Published in

Case reports in urology. Volume 2026. Pages 3596493. Epub Jul 22, 2026.

Abstract

Primary melanoma is a very rare malignancy arising from the kidney. We present a case of a 78-year-old female who presented with locally advanced primary kidney melanoma requiring complex surgical intervention and multidisciplinary management. The patient underwent an open left radical nephrectomy with distal pancreatectomy, splenectomy, and colonic resection, followed by adjuvant immunotherapy. We additionally review the literature regarding the diagnosis and management of primary renal melanoma.

PMID:
42488406
Bibliographic data and abstract were imported from PubMed on 23 Jul 2026.

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