Beyond the Valve Itself: Extra-valvular Phenotyping in Mitral Stenosis: A Novel Pathophysiology-driven Echocardiographic Staging System.

Authors

Gabriele Cordoni, Dania Mohty, Anastasia Shchendrygina, Domenico Galzerano, Hani Al Sergani, Giovanni Di Salvo, Valeria Pergola

Published in

European cardiology. Volume 21. Pages e39. Epub Jul 09, 2026.

Abstract

Current guideline-based classifications of mitral stenosis rely primarily on parameters ofvalvular narrowing and its associated clinical symptoms. In recent years, novel phenotyping approaches based on the concept of sequential cardiac chamber involvement have been developed for other cardiovascular conditions, including mitral regurgitation, aortic stenosis, and heart failure with preserved ejection fraction. Similarly, the development of an extra-valvular echocardiographic staging system for mitral stenosis, grounded in the extent of cardiac chamber involvement, appears warranted to improve risk stratification and tailor clinical management.

PMID:
42488773
Bibliographic data and abstract were imported from PubMed on 23 Jul 2026.

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