Authors
Dandan Lin, Bo Zhu, Shengya Liu, Chang Lu, Pinghui Wu, Borong Wen, Binglou He, Hanping Li, Yongjian Liu, Lei Jia, Bohan Zhang, Xiaolin Wang, Jingyun Li, Jingwan Han, Junjun Jiang, Lin Li
Published in
AIDS research and human retroviruses. Pages 8892229261471606. Jul 23, 2026. Epub Jul 23, 2026.
Abstract
Recombination events are a key driver of human immunodeficiency virus type 1 (HIV-1) genetic diversity. In this study, HIV-1 samples were collected from two male patients in Shenzhen, China. Two novel recombinant forms (Ls6449 and Ls16801) derived from CRF01_AE and CRF07_BC were identified, and their near full-length genomes were obtained. Analysis of these two forms suggested that the recombination between CRF01_AE and CRF07_BC continued to occur in Shenzhen, potentially contributing to the increasing genetic complexity of the local HIV-1 epidemic. These findings highlight the need for enhanced molecular surveillance and genotyping targeting key routes, specifically sexual transmission and mobility-associated spread. It is expected to generate precise epidemiological evidence and inform local HIV prevention and control strategies.
PMID:
42494083
Bibliographic data and abstract were imported from PubMed on 24 Jul 2026.
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