Auer rod-like inclusions in marginal zone lymphoma: a potential diagnostic pitfall.

Authors

Nour Louati, Imen Krichen, Ines Jedidi, Ikram Ben Amor

Published in

Journal of hematopathology. Volume 19. Issue 1. Jul 24, 2026. Epub Jul 24, 2026.

Abstract

A 47-year-old man presented with leukocytosis and absolute lymphocytosis. Peripheral blood smear examination revealed atypical lymphoid cells containing striking Auer rod-like cytoplasmic inclusions, creating a strong morphologic impression of acute promyelocytic leukemia. However, flow cytometry demonstrated a mature monoclonal B cell population lacking myeloid differentiation, and bone marrow biopsy established the diagnosis of marginal zone lymphoma. This rare case highlights a major diagnostic pitfall and underscores that Auer rod-like inclusions are not exclusively restricted to myeloid neoplasms.

PMID:
42496960
Bibliographic data and abstract were imported from PubMed on 24 Jul 2026.

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