Molecular epidemiology of human rhinovirus in coastal China: genotyping and epidemic trends in Daishan (2022-2023).

Authors

Jiwei Shu, Jing Wang, Zhe Huang, Yu Zhang, Cheng Liu

Published in

Virus genes. Jul 26, 2026. Epub Jul 26, 2026.

Abstract

To investigate the positive rate and molecular epidemiological characteristics of human rhinovirus (HRV) in influenza-like illness (ILI) cases in Daishan, Zhejiang Province. Throat swab specimens from ILI cases were collected from a hospital in Daishan, Zhejiang Province, between January 2022 and December 2023. Real-time PCR was performed to identify 14 common respiratory pathogens. Nested PCR was performed to amplify the VP4/VP2 gene sequences of HRV-positive specimens. Phylogenetic analyses were conducted based on the VP4/VP2 regions of HRV. A total of 1,255 specimens were collected. The overall positive rate for respiratory pathogens was 54.34% (682/1,255), with HRV detected in 7.57% (95/1,255) of the cases. Three genotypes of HRV were identified, encompassing 25 serotypes, including 15 types of HRV-A, 5 types of HRV-B, and 5 types of HRV-C. HRV was one of the main pathogens causing respiratory tract infections in Daishan, Zhejiang Province, from January 2022 to December 2023. The prevalence of HRV was complex, with HRV-A being the predominant genotype, while HRV-A, HRV-B, and HRV-C were co-prevalent. Continuous monitoring of HRV infections is recommended.

PMID:
42502147
Bibliographic data and abstract were imported from PubMed on 26 Jul 2026.

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