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Multiparametric cardiovascular magnetic resonance for differentiating cardiac masses: clinical impact from a case series.

Created on 28 Jul 2026

Authors

Mauricio Garcia-Cardenas, Ana Karen Nieto-Dolores, Jonathan Iram Valenzuela-Sanchez, Michelle Valle-Rodriguez, Alfonso Gonzalez-Trejo, Adriana Dominguez-Linares, Enrique Ruiz-Mori, Nilda Espinola-Zavaleta

Published in

European heart journal. Case reports. Volume 10. Issue 7. Pages ytag532. Epub Jul 15, 2026.

Abstract

Cardiac masses represent a rare but clinically significant diagnostic entity. Morphological assessment alone is often insufficient for definitive diagnosis. Cardiovascular magnetic resonance (CMR) provides comprehensive tissue characterization.
We present a case series illustrating the heterogeneous spectrum of cardiac masses encountered in both oncologic and non-oncologic patients. Clinical scenarios included intracardiac metastases, tumour-related thrombus, bland thrombi, and benign primary tumours, such as rhabdomyoma and myxoma. In all cases, CMR was pivotal for tissue characterization using multiparametric assessment.
This series highlights the limitations of morphology-based assessment and emphasizes the value of a structured multiparametric CMR approach. Key features, such as perfusion, enhancement pattern, tissue heterogeneity, and infiltrative behaviour, allow reliable differentiation between thrombi and neoplastic lesions. Beyond illustrating individual cases, this series proposes a structured multiparametric CMR algorithm applicable across diverse clinical scenarios, emphasizing its role in medical practice and diagnostic decision-making.

PMID:
42516944
Bibliographic data and abstract were imported from PubMed on 28 Jul 2026.

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