Hiring in life sciences? Share your open positions with our professional community. Read more Close

Advertisement

Advanced cartilage damage and radiographic osteoarthritis are associated with inferior outcomes and higher rates of conversion to total hip arthroplasty after hip labral reconstructions: A systematic review.

Created on 28 Jul 2026

Authors

Ozgur Basal, Furkan Karakas, James G Jefferies, Jure Serdar, Baris Kocaoglu, Mahmut Nedim Doral

Published in

Journal of experimental orthopaedics. Volume 13. Issue 3. Pages e70812. Epub Jul 27, 2026.

Abstract

Hip labral reconstruction survival refers to the durability of the reconstructed labrum, typically measured by the rate of freedom from revision surgery or conversion to total hip arthroplasty (THA) over time. This systematic review aimed to identify and combine prognostic factors, particularly those related to cartilage status, graft characteristics, and osteoarthritis, that are associated with functional outcomes and long-term survivorship after hip labral reconstruction.
Clinical studies reporting prognostic/exposure factors (e.g., cartilage status, osteoarthritis severity and graft/technique variables) and postoperative outcomes in adult patients undergoing hip labrum reconstruction were searched in PubMed and Scopus databases up to December, 2025. Two reviewers performed the search, data extraction, and risk of bias assessment using ROBINS-I. Random-effects meta-analyses and meta-regressions were performed when ≥2 studies provided comparable data.
Thirty-two studies (2252 hips) were included. Patient-reported outcomes showed significant improvement across cohorts after reconstruction, but survival not requiring arthroplasty varied depending on joint status and technique. In a random-effects meta-analysis, the pooled THA conversion rate was 8.8% (95% CI: 6.7%-11.5%). In meta-regression, a higher prevalence of high-grade acetabular cartilage damage was associated with increased THA conversion (univariate p = 0.035; β = 0.0269, p = 0.0165 after adjusting for follow-up time), and longer follow-up time independently increased the risk of conversion (β = 0.0300/month, p = 0.0082). In exploratory subgroup analyses, circumferential reconstruction was associated with greater PROM recovery and a lower pooled THA conversion rate than segmental techniques, and allografts were associated with a lower pooled THA conversion rate than autografts; these comparisons are confounded by surgeon experience, institutional volume, and indication, and should be regarded as hypothesis-generating only.
Outcomes after hip labral reconstruction appear to be associated with preoperative joint status, particularly cartilage damage and radiographic osteoarthritis. These findings are derived from study-level analyses and should not be interpreted as evidence of independent or causal effects. Apparent differences between graft types and reconstruction configurations are exploratory and likely reflect underlying confounding rather than true treatment effects. Capsular management and concomitant cartilage procedures were not consistently associated with differences in clinical outcomes or THA conversion.
Level IV, systematic review and meta-analysis of Level IV-III studies. Systematic review registration: This systematic review was prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO). Registration number: CRD420251273992. Available at: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251273992.

PMID:
42516985
Bibliographic data and abstract were imported from PubMed on 28 Jul 2026.

Read full publication at:
Please sign in to see all details.

Advertisement

Stats

  • Community rating n/a 0 votes
  • Reviewers' rating n/a 0 votes
  • Your rating

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

  • Recommendations n/a n/a positive of 0 vote(s)
  • Views 3
  • Comments 0

Recommended by

  • No recommendations yet.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.

Advertisement