L-Dopa-asparagine-derived carbon dots as a targeted theranostic agent for melanoma.

Authors

Debolina Basu, Afreen Zaman, Prasanta Kumar Das

Published in

Chemical communications (Cambridge, England). Jul 28, 2026. Epub Jul 28, 2026.

Abstract

L-Dopa-asparagine-derived carbon dots (DACDs) were developed for the preferential diagnosis and targeted therapy of melanoma. DACD exhibited ∼2.8-fold and clioquinol (FIH-1 inhibitor)-loaded DACD exhibited ∼3.3-fold greater cytotoxicity towards B16F10 than NIH3T3 cells via enhanced hypoxia and ROS-induced apoptosis during the conversion of L-dopa to melanin.

PMID:
42517688
Bibliographic data and abstract were imported from PubMed on 28 Jul 2026.

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