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Clinical and biomechanical recovery trajectories during anti-gravity treadmill-assisted rehabilitation after complex lower-limb articular fractures: a prospective pilot cohort study.

Created on 29 Jul 2026

Authors

Belinda Trobec, Gianluca Canton, Lorenzo Scarpi, Giulia Sgubin, Edoardo De Pol, Michelangelo Scordo, Alex Buoite Stella, Manuela Deodato, Luigi Murena, Chiara Ratti

Published in

Disability and rehabilitation. Pages 1-8. Jul 29, 2026. Epub Jul 29, 2026.

Abstract

While previous research has established the clinical applicability of anti-gravity treadmill (AGT)-assisted rehabilitation after lower-limb fracture fixation, longitudinal biomechanical recovery in patients with complex AO/OTA C3 tibial plateau and pilon fractures remains poorly understood.
This prospective single-center cohort study included 17 adults (18-65 years) who underwent ORIF for AO/OTA C3 tibial plateau (n = 8) or pilon fractures (n = 9), followed by a structured AGT-assisted rehabilitation program. Independence in activities of daily living (ADLs), return to work and sport, radiographic outcomes, and gait analysis were assessed at 6 weeks, 3 months, and 6 months.
Pain, ADLs, weight-bearing, and gait symmetry improved throughout follow-up. No mechanical complications, loss of reduction, or hardware failure were observed. ADL independence was achieved by 94% of patients at 6 weeks and by all at 3 months. Pilon fractures showed earlier restoration of loading symmetry, whereas tibial plateau fractures reached comparable values by 6 months. Gait analysis demonstrated progressive normalization of loading symmetry.
This pilot study provides preliminary longitudinal clinical and laboratory-based biomechanical data on recovery after complex tibial plateau and pilon fractures managed within an AGT-assisted rehabilitation pathway. However, without a control group, the observed improvements cannot be attributed specifically to AGT.

PMID:
42522462
Bibliographic data and abstract were imported from PubMed on 29 Jul 2026.

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