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Synthesis of triarylmethanes via a three-component decarboxylative Friedel-Crafts reaction.

Created on 29 Jul 2026

Authors

Jian Wang, Jianming Xu, Yao Wang, Yifan Cao, Zhiqiang Chen, Sufan Gao, Ying Xie, Yulong Li, Chenyi Li

Published in

Organic & biomolecular chemistry. Jul 29, 2026. Epub Jul 29, 2026.

Abstract

A Lewis acid-catalyzed, one-pot, three-component direct decarboxylative Friedel-Crafts reaction among benzofuran-derived azadienes, isatoic anhydride, and alcohols has been disclosed. A series of potentially useful triarylmethanes containing a benzofuran-fused moiety were synthesized in good to excellent yields. The scalability of this reaction and the transformability of its products demonstrate the utility of this method.

PMID:
42522675
Bibliographic data and abstract were imported from PubMed on 29 Jul 2026.

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