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A cross-sectional study of pulpal oxygen saturation in permanent incisors affected by molar incisor hypomineralisation (MIH).

Created on 29 Jul 2026

Authors

T C de Almeida Dos Santos, M J D Gallo, A B de Souza Ramos, A A Leandro Junior, A De Rossi, F W G de Paula E Silva, M D Sousa-Neto, C Estrela, F K de Carvalho, A M de Queiroz

Published in

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry. Jul 29, 2026. Epub Jul 29, 2026.

Abstract

To evaluate pulpal oxygen saturation (SaO₂) in permanent incisors affected by molar incisor hypomineralisation (MIH) compared with sound permanent incisors in children.
This cross-sectional study included 112 MIH-affected and 112 sound permanent incisors from children aged 6-12 years. Clinical examination was performed in all teeth, and periapical radiographs were obtained for MIH-affected incisors to exclude pathology and assess root development. Pulpal oxygen saturation was measured using pulse oximetry. Data were analysed using a mixed-effects linear model accounting for clustering of multiple teeth within the same individual. Complementary non-parametric analyses were also performed.
MIH-affected incisors showed lower SaO₂ than controls (mean difference: 1.37%; 95% CI 0.90-1.84; p < 0.001). The intraclass correlation coefficient (ICC = 0.18) indicated moderate within-subject clustering. No significant differences in SaO₂ were observed according to root development stage (p = 0.45).
MIH-affected incisors exhibited slightly lower SaO₂ compared with sound teeth. Although statistically significant, the small magnitude of this difference limits its immediate clinical relevance and should be interpreted with caution.

PMID:
42525187
Bibliographic data and abstract were imported from PubMed on 29 Jul 2026.

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