Authors
Weixin Li, Mayte Suarez-Farinas, Alessandra Shuster, Sara Mednick, Mariana G Figueiro
Published in
Journal of applied gerontology : the official journal of the Southern Gerontological Society. Pages 7334648261474211. Jul 29, 2026. Epub Jul 29, 2026.
Abstract
BackgroundLight offers a promising approach to sleep and circadian disturbances in mild cognitive impairment (MCI).ObjectiveTest a home-based lighting intervention in people living with MCI.MethodsIn a randomized, placebo-controlled trial, 61 participants received active or placebo light for 24 weeks, with assessments for cognition, sleep, depression, and quality of life at baseline, week 13, 25, and, post-intervention, at week 37. Light exposure was measured as area under the curve (AUC) for morning circadian stimulus (CS).ResultsActive light participants (mean age 69.7 years; 52% male; mean MoCA 21.4) showed greater improvement in ADAS-Cog memory scores than placebo (p = 0.035), higher morning CS AUC by week 25 (0.021 vs -0.030; p = 0.025), and better sleep percent (-0.21 vs -1.29; p = 0.042), wake percent (-0.10 vs 1.19; p = 0.023), and wake after sleep onset (2.19 vs 8.23 min; p = 0.031).
PMID:
42527889
Bibliographic data and abstract were imported from PubMed on 30 Jul 2026.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 4
- Comments 0