Risk Stratification in Cardiovascular Medicine for Prognostic Assessment and Therapeutic Decision-Making: From Atrial Fibrillation to the Broader Disease Spectrum.

Authors

Yuichi Saito, Kazuya Tateishi, Ken Kato, Hideki Kitahara, Yoshio Kobayashi

Published in

Journal of arrhythmia. Volume 42. Issue 4. Pages e70435. Epub Jul 29, 2026.

Abstract

Risk stratification using validated scoring systems is fundamental to contemporary cardiovascular medicine, underpinning diagnosis, treatment selection, and prognostic assessment. This review provides a comprehensive overview of the major risk scores used across a broad spectrum of cardiovascular diseases, such as atrial fibrillation, acute coronary syndrome, and others, highlighting their development, clinical applications, and evolving roles in guideline-directed care. Importantly, predictive performance alone does not guarantee clinical benefit. We therefore examine evidence from randomized implementation trials evaluating whether risk score-guided management improves clinical outcomes and discuss the future role of artificial intelligence in reshaping cardiovascular risk assessment by integrating dynamic, individualized prediction with actionable clinical decision support.

PMID:
42529449
Bibliographic data and abstract were imported from PubMed on 30 Jul 2026.

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