Cryoablation as an organ-preserving therapy for low rectal cancer a comprehensive protocol and institutional perspective.

Authors

Xuejun Jiang, Feng Zhou, Zujin Ji, Xinyi Lei, Fangjun Yuan

Published in

Frontiers in oncology. Volume 16. Pages 1757590. Epub Jul 16, 2026.

Abstract

Cryoablation is an interventional approach which induces localized tumor destruction. It is used to treat patients with low rectal cancer (LRC) to preserve their sphincters and avoid permanent colostomies. This article provides a systematic illustration of cryoablation for LRC, encompassing its core technical principles, indications and contraindications. Furthermore, it elaborates on pre-procedural preparation, standardized operative steps, post-cryoablation management, potential complications and mitigation and long-term follow-up protocols. Rooted in five decades of institutional experience, we seek to standardize the procedure and establish it as a credible, evidence-based alternative approach for well-selected patients, especially those who are not candidates for or who decline radical resection.

PMID:
42534769
Bibliographic data and abstract were imported from PubMed on 31 Jul 2026.

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