Local Prevalence of Ceftriaxone Resistance Informs Optimal Deployment of New Gonorrhea Treatments.

Authors

Kirstin I Oliveira Roster, Minttu M Rönn, Eva R Gorenburg, Dennis K Partl, Nanina Anderegg, Pia Abel Zur Wiesch, Carmen Au, Roger D Kouyos, Fernando P Martinez, Nicola Low, Yonatan H Grad

Published in

Open forum infectious diseases. Volume 13. Issue 7. Pages ofag447. Epub Jul 18, 2026.

Abstract

Numerous factors may influence the optimal rollout of new gonococcal antibiotics. We compared 8 rollout strategies using a gonorrhea transmission model and ranked strategies by the number of gonococcal infections and clinically useful antibiotic lifespan. Rankings were most sensitive to the starting ceftriaxone resistance prevalence and screening frequency.

PMID:
42534456
Bibliographic data and abstract were imported from PubMed on 31 Jul 2026.

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