Authors
Mehmoona Sharif, Umme Habiba Saeeda, Aneela Nawaz, Muhammad Farman, Malik Badshah, Aamer Ali Shah, Muniba Jadoon, Lolakhon Ettibaeva, Samiullah Khan
Published in
Food science and biotechnology. Volume 35. Issue 9. Pages 2613-2626. Epub Jun 08, 2026.
Abstract
Phellinus gilvus has potent antioxidant and antimicrobial activities, but the exact bioactive components are unknown. The study investigated P. gilvus and unveiled six novel compounds as its principal antimicrobial agents. Hexane fraction exhibited antibacterial activity against S. aureus (19 ± 0.57 mm) and B. subtilis (17 ± 0.57 mm) at a minimum inhibitory concentration of 31.25 µg/mL. The ethyl acetate fraction showed antifungal activity with inhibitory zones of 21 ± 1.52 mm against C. albicans, 15 ± 1.00 mm against A. niger, and 17 ± 1.00 mm against A. flavus. Most extracts possessed antioxidant potential with a maximum percent of 78 ± 1.00% by the ethyl acetate fraction. Cytotoxic and hemolytic activity was within an acceptable range and confirmed the safety profile for the fractions. The metabolic profile revealed polysaccharides, quinones, and triterpenes, emphasizing the potential of P. gilvus as a promising source for developing novel antifungal and antibacterial agents.
The online version contains supplementary material available at 10.1007/s10068-026-02199-5.
PMID:
42534725
Bibliographic data and abstract were imported from PubMed on 31 Jul 2026.
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