Authors
Fereshteh Sattar, Marzieh Taheri, Pedram Babaei, Ehsan Shirvani, Hamidreza Roohafza, Faezeh Tabesh, Mohammad Hadi Mansouri, Mohammadmahdi Hadavi, Anahita Babak, Sina Rouhani, Masoumeh Sadeghi
Published in
Future cardiology. Pages 1-8. Aug 01, 2026. Epub Aug 01, 2026.
Abstract
Center-based cardiac rehabilitation (CR) is the standard of care for patients with cardiovascular disease. However, access limitations have led to increased interest in home-based alternatives. This study aimed to compare the effects of home-based and center-based CR in an Iranian population.
In this randomized controlled trial, 236 patients with cardiovascular disease were randomized to receive either home-based (n = 107) or center-based (n = 129) CR. Interventions lasted 8 weeks, with outcomes assessed at baseline and 6 months. The primary outcome was the change in exercise capacity. Secondary outcomes included exercise capacity, maximum heart rate, blood pressure (BP), lipid profile, fasting blood sugar, body mass index, and waist circumference.
Between-group analysis using ANCOVA, adjusting for baseline values, showed that center-based CR was significantly more effective in improving exercise capacity (11.49 ± 0.22 vs 13.65 ± 0.19, p < 0.001), systolic BP (122.08 ± 1.33 vs 116.58 ± 1.17, P = 0.005), and diastolic BP (79.83 ± 0.84 vs 74.35 ± 0.74, p < 0.001). No significant between-group differences were observed in other variables.
Both home-based and center-based CR improved exercise capacity; however, center-based CR achieved superior gains and better blood pressure control. Home-based CR may be a practical alternative when access to supervised programs is limited.
www.IRCT.iridentifier:IRCT20201028049181N1.
PMID:
42538869
Bibliographic data and abstract were imported from PubMed on 01 Aug 2026.
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