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[A new lignan from Cinnamomum longepaniculatum with antioxidant activity].

Created on 03 Aug 2026

Authors

Li-Jun Zheng, Le Ouyang, Hai-Ying Wu, Li-Bin Xu, Si-Rong Lin, Wen-Jie Chi, Lin Ni

Published in

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. Volume 51. Issue 12. Pages 3444-3449.

Abstract

The chemical constituents of Cinnamomum longepaniculatum leaves were isolated and purified using separation techniques such as silica gel column chromatography, macroporous adsorption resin, gel column chromatography, and preparative high-performance liquid chromatography. The isolated compounds were identified by combining spectroscopic techniques including high-resolution electrospray ionization mass spectrometry(HR-ESI-MS), nuclear magnetic resonance(NMR), ultraviolet spectroscopy(UV), and infrared spectroscopy(IR) and literature data. A total of nine compounds were identified: cinlongeligan A(1), salicifoneoliganol(2),(-)-syringaresinol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside(3), syringaresinol mono-β-D-glucoside(4), episyringaresinol-4″-O-β-D-glucopyranoside(5),(+)-medioresinol 4'-O-β-D-glucopyranoside(6), lyoniside(7), lantibetin(8),(+)-isolariciresinol-9-O-β-D-glucoside(9). Compound 1 was a novel lignan derivative. Except for compounds 7 and 9, all others were isolated from the genus Cinnamomum for the first time. The results of antioxidant activity showed that compounds 1 and 3 had significant scavenging capacity against 2,2-diphenyl-1-picrylhydrazyl(DPPH) free radical with IC_(50) values of(10.35±0.46) and(9.73±0.62) μg·mL~(-1), respectively.

PMID:
42543303
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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