[The diagnostic complexity of paraneoplastic thrombotic thrombocytopenic purpura].

Authors

Axelle Delcour, Laurent Jadot, Nassim Aït Moussa, Lyonel Herman, Quentin Perlot

Published in

Revue medicale de Liege. Volume 81. Issue 7-8. Pages 415-419.

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a rare microangiopathy characterized by mechanical hemolytic anemia, thrombocytopenia, and multiorgan dysfunction, resulting from a severe deficiency of ADAMTS13. Among its rare forms, paraneoplastic TTP remains poorly described. We report here the case of a patient in the intensive care unit presenting with paraneoplastic TTP associated with metastatic prostate cancer. This case illustrates the diagnostic challenge posed by the interplay of multiple mechanisms and allows discussion of the different therapeutic options according to the type of TTP, including the role of plasma exchange in paraneoplastic TTP.

PMID:
42544062
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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