Clinical outcomes of 295 PICC-ports implanted in cancer patients: A retrospective cohort study.

Authors

Mathieu Leconte, Nicolas Beaufrère, Marion Warembourg, Aubin Hillaireau, Tristan Roziere, Pascal Fangio

Published in

The journal of vascular access. Pages 11297298261471393. Aug 02, 2026. Epub Aug 02, 2026.

Abstract

PICC-ports are emerging as an alternative long-term vascular access device in oncology. However, real-world outcome data remain limited. We evaluated device survival and complication rates in a tertiary center using a standardized bundle for PICC-port insertion.
We conducted a retrospective cohort study at a tertiary vascular access center in France including 295 PICC-ports implanted in adult oncology patients between November 2023 and October 2025. Devices were inserted by anesthesiologists and specialized vascular access nurses according to the SIP-Port protocol. Data collected included demographics, cancer type, catheter dwell time, early and late complications, and device failures defined as removals due to device-related complications. Device survival was evaluated using Kaplan-Meier analysis.
A total of 72,344 catheter-days were recorded. Mean and median device dwell times were 245.2 and 280 days respectively. The cohort consisted of 138 men (46.8%) and 157 women (53.2%), with a mean age of 64.4 years. The most common malignancies were breast cancer (28.1%), lung cancer (23.7%), and head and neck cancer (16.9%). Infection incidence was 0.15 per 1000 catheter-days and symptomatic catheter-related thrombosis occurred at 0.16 per 1000 catheter-days. Twenty-four devices (8.1%) were removed due to serious adverse events. Device survival free from serious adverse events at 365 days was 91.2%.
PICC-ports implanted by trained vascular access specialists demonstrated excellent device survival and low complication rates. These findings support the safety and reliability of PICC-ports as long-term vascular access devices for oncology patients when inserted and maintained using standardized protocols.

PMID:
42543764
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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