Mediating Effects of Fear of Movement and Self-Efficacy Between Illness Perception and Health-Related Quality of Life in Pulmonary Hypertension.

Authors

Juanjuan Xiong, Yiru Zhai, Aiyun Yu, Liting Wang, Zeqi Zheng, Qiong Yan

Published in

Psychology research and behavior management. Volume 19. Pages 617450. Epub Jul 29, 2026.

Abstract

The purpose of this study was to investigate the mediating effects of fear of movement and self-efficacy on the relationship between illness perception and health-related quality of life (HRQOL) in patients with pulmonary hypertension (PH).
From July 2025 to February 2026, patients with PH were enrolled from the outpatient clinics or wards at two campuses of a tertiary hospital in Nanchang, China, using a convenience sampling method. For each patient, a range of data, including sociodemographic and clinical information, and validated scales assessed for illness perception, self-efficacy, fear of movement, and HRQOL were collated to examine the interaction. The mediation analysis was carried out with the PROCESS macro in SPSS.
185 patients with PH were investigated with structured questionnaires. The mediation analysis showed that illness perception had a significant total effect on HRQOL. Additionally, the significant indirect effects of illness perception on HRQOL were mediated by fear of movement respectively, accounting for 16.4% and 8.7% of the total effect. We also observed that fear of movement and self-efficacy sequentially mediated the relationship between illness perception and HRQOL, which accounted for 4.6% of the total effect.
Fear of movement and self-efficacy were multiple mediators of the relationship between illness perception and HRQOL among patients with PH. This highlights the importance of fear of movement and self-efficacy. Thus, potential clinical interventions targeted for strengthening self-care efficacy and relieving fear of movement may be beneficial for the improvement of HRQOL.

PMID:
42544210
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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