Incidental Detection of Remote Ictal Hypermetabolism on FDG PET/CT Following Brain Metastatectomy : A Rare Diagnostic Pitfall.

Authors

Nivedita Kundu, Dikhra Khan, Sambit Sagar, Rakesh Kumar

Published in

Clinical nuclear medicine. Jul 24, 2026. Epub Jul 24, 2026.

Abstract

FDG PET/CT is widely used in oncology but may occasionally show non-neoplastic hypermetabolic processes. We report incidental detection of probable ictal/peri-ictal hypermetabolism on follow-up FDG PET/CT in a 39-year-old woman with treated breast carcinoma and prior left temporal metastatectomy. Imaging demonstrated a postoperative cavity in the left temporal lobe and a focal intensely FDG-avid cortical area in the left posterior parietal region without CT correlate or other evidence of active systemic disease. The imaging pattern favored seizure-related cortical hypermetabolism rather than tumor recurrence. Recognition of this uncommon pitfall is important to avoid false-positive interpretation and inappropriate upstaging.

PMID:
42545346
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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