Authors
Hye Young Hong, Eun Young Kim, A La Woo, Song Yee Kim, Young Ho Yang, Ha Eun Kim, Jin Gu Lee, Moo Suk Park
Published in
Annals of medicine. Volume 58. Issue 1. Pages 2705636. Epub Aug 03, 2026.
Abstract
Lung transplantation (LT) is the only definitive treatment for end-stage lung diseases; however, patients often experience psychiatric problems that can affect post-transplant recovery. Although postoperative delirium frequently occurs, its risk factors and influence on mortality are not well established. This study aimed to evaluate the incidence of LT-associated psychiatric issues and analyse the association of delirium with mortality.
Retrospective cohort study.
Patients who underwent LT between January 2013 and March 2023.
We reviewed the incidence of psychiatric conditions before and after LT. Logistic regression analysis identified risk factors for postoperative delirium, and survival analysis was conducted.
Pre-transplant psychiatric assessments revealed mild anxiety and depression among 398 patients. Notably, 45% of patients experienced delirium after LT. Patients with a higher body mass index (BMI), longer operation duration and high Beck Anxiety Inventory scores exhibited an increased risk of postoperative delirium. Furthermore, patients who developed postoperative delirium had a higher 2- and 5-year mortality rate.
The findings revealed that pre-transplant anxiety, high BMI and prolonged operative duration increase the risk of postoperative delirium risk, which in turn affects long-term mortality. Comprehensive psychiatric evaluation and targeted management are essential for improving post-transplant outcomes.
PMID:
42544909
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.
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