[Advances in the Study of Factors Influencing the Efficacy of CAR-T Cell Therapy in Hematologic Oncology Treatment--Review].

Authors

Li-Mei Li, Xun Lai, Hong-Jing Yin

Published in

Zhongguo shi yan xue ye xue za zhi. Volume 34. Issue 3. Pages 910-916.

Abstract

Chimeric antigen receptor T cell (CAR-T) therapy is a revolutionary progress in the current field of tumor treatment, especially showing remarkable potential in relapsed/refractory hematological malignancies. However, there are significant differences in efficacy among different patients, and such differences are affected by multiple clinical and biomedical factors. This review will discuss the current application status of CAR-T therapy in hematological malignancies, analyze the key factors influencing the efficacy, and summarize the latest research trends and development directions in this field, so as to provide references for clinical decision - making and scientific research innovation.

PMID:
42544685
Bibliographic data and abstract were imported from PubMed on 03 Aug 2026.

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