Autism spectrum disorder: has it lost its meaning and is it leading to misdiagnosis?

Authors

Uta Frith

Published in

Psychological medicine. Volume 56. Pages e240. Aug 04, 2026. Epub Aug 04, 2026.

Abstract

Since the 1940s, the concept of autism has undergone marked changes, and autism spectrum disorder (ASD) is a wildly heterogenous condition. At the same time, the prevalence of ASD has increased massively.
This essay considers possible reasons for the changes and their consequences.
Among drivers for the increase in prevalence are cultural changes, such as the desire for inclusion, harm avoidance, reliance on self-report, and the acceptance of masking. These have all led to a lowering of the diagnostic threshold. Furthermore, the popularity of the concept of autism boosted numbers via self-diagnosis and a search for identity.
Marked differences now exist between those first diagnosed in childhood and others first diagnosed in adolescence or adulthood. The time has come to examine reasons for these conceptual changes and the consequences for clinical practice and research.

PMID:
42548172
Bibliographic data and abstract were imported from PubMed on 04 Aug 2026.

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