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Vector-enabled metagenomics reveals the first detection of the geminivirus beet curly top Iran virus in Europe.

Created on 04 Aug 2026

Authors

Laura Miozzi, Silvia Rotunno, Fulco Frascati, Monica Marra, Francesco Nugnes, Umberto Bernardo, Daniele Marian, Sofia Bertacca, Massimiliano Ballardini, Gian Paolo Accotto, Anna Maria Vaira, Emanuela Noris

Published in

The Journal of general virology. Volume 107. Issue 8.

Abstract

Geminiviruses are among the most threatening emerging insect-borne viruses and are responsible for serious outbreaks worldwide. Climate change (i.e. higher temperatures) could further exacerbate their impact on crops, highlighting the need for new diagnostic approaches to manage potentially dangerous situations. vector-enabled metagenomics (VEM) exploits the natural ability of highly mobile insects to accumulate viruses acquired from plants over time and space within an ecosystem; this approach is effective for monitoring the presence of new invasive or indigenous viruses in large areas. Geminiviruses have circular ssDNA genomes that can be readily targeted by rolling circle amplification (RCA). The combination of RCA and VEM largely increases the chances of detecting geminiviruses. This approach enabled us to identify the becurtovirus beet curly top Iran virus (BCTIV, Becurtovirus betae) in insects collected in Europe. BCTIV is a major pathogen of sugar beet but can also infect plants of other families; it is transmitted by cicadellids and has so far been detected only in Iran and Anatolia (Turkey). We also show that two cucurbit species, watermelon (Citrullus lanatus) and zucchini (Cucurbita pepo) are both natural and experimental hosts for BCTIV.

PMID:
42550599
Bibliographic data and abstract were imported from PubMed on 04 Aug 2026.

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