Authors
A Outahayou, I Fellat, S Bensaleh, N El Karroumi, W Amara, M Monchi, C Moini
Published in
Annales de cardiologie et d'angeiologie. Aug 04, 2026. Epub Aug 04, 2026.
Abstract
Out-of-hospital cardiac arrest is a major public health challenge in France, with approximately 46,000 cases per year and survival rates ranging from 4 to 10%. Early prehospital management is a key determinant of vital and neurological prognosis.
Single-center, retrospective, observational study including 100 patients managed by the mobile intensive care unit of Melun General Hospital between January 2021 and September 2025. Neurological outcome was assessed using the Cerebral Performance Category score. Bivariate analysis and multivariate logistic regression were performed to identify factors associated with in-hospital survival. Numerical variables are reported as median [quartile1-quartile 3].
Median age was 66 years [54.5-73], with 59% male patients. Cardiac arrest occurred at home in 78% of cases. Bystander cardiopulmonary resuscitation was initiated in 80% of cases; public automated external defibrillator use remained marginal (9%). Median no-flow duration was 3minutes [1-8.5] and median low-flow duration was 20minutes [13-30]. Asystole was the initial rhythm in 76% of cases. In-hospital survival was 20%. Multivariate analysis showed that shorter no-flow and low-flow intervals were independently associated with survival. Bystander intervention was not significant after adjustment.
Prehospital time intervals, especially no-flow duration, are the primary determinants of survival after out-of-hospital cardiac arrest. Strengthening public training in basic life support and improving automated external defibrillator accessibility are priority targets to improve outcomes.
PMID:
42552213
Bibliographic data and abstract were imported from PubMed on 05 Aug 2026.
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