The Impact of Donor RBC Storage Duration on the Efficacy of Chronic RBC Exchange.

Authors

Jaehyup Kim

Published in

Journal of clinical apheresis. Volume 41. Issue 4. Pages e70163.

Abstract

Red blood cells (RBCs) accumulate damage during storage, shortening their post-transfusion lifespan. For chronic RBC exchange (RBCx), fresh RBCs have been preferred because of this concern. This study assessed the impact of RBC storage time and analyzed 20 procedures using freshness-waived RBCs. The results confirmed a reduction in calculated RBC lifespan. However, the impact on hematocrit or HbS percentage was not significant. Extending RBC freshness criteria for chronic RBCx could reduce costs while maintaining similar outcomes.

PMID:
42554130
Bibliographic data and abstract were imported from PubMed on 05 Aug 2026.

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