A novel alkaloid and eight compounds from Portulaca oleracea L. and their biological activities.

Authors

Pengyan Liu, Xinyi Zhao, Xiujuan Lan, Xiyue Gao, Xixiang Ying, Fan He, Zheming Ying

Published in

Natural product research. Pages 1-6. Aug 05, 2026. Epub Aug 05, 2026.

Abstract

A study on Portulaca oleracea L. resulted in the identification of a previously undescribed amide derivative, oleracrylimide G (1), along with eight known metabolites. The full structural assignments were achieved using comprehensive spectroscopic data. Assays demonstrated that oleracrylimide G (1) exerts significant anti-inflammatory effects, markedly inhibiting the secretion of IL-1β and IL-6 in LPS-induced inflammatory models at a concentration of 20 μM. These results reveal that the compound possesses potent anti-inflammatory activity.

PMID:
42555858
Bibliographic data and abstract were imported from PubMed on 06 Aug 2026.

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