Super-electrophilic Lewis acid, Et₃Si⁺[HCB₁₁H₅Cl₆]^-, as an effective catalyst for ring-opening rearrangements of fluorinated cyclopropanes.

Authors

Nikita A Sokolov, Angelina Yu Bobrova, Ilya V Prolomov, Michael G Medvedev, Julia V Burykina, Maxim A Novikov, Roman A Novikov, Yury V Tomilov

Published in

Organic & biomolecular chemistry. Aug 05, 2026. Epub Aug 05, 2026.

Abstract

Et₃Si[HCB₁₁H₅Cl₆] was proved to be a highly effective catalyst to induce cyclopropyl-to-allyl rearrangements of gem-difluorocyclopropanes, allowing facile reductive Friedel-Crafts alkylations of arenes using Et₃SiH as a stoichiometric reductant. The general patterns determining the chemo- and regioselectivities of the process, by fine-tuning the reactivity of 2-fluoroallyl and vinyl carbocationic intermediates, were determined.

PMID:
42555841
Bibliographic data and abstract were imported from PubMed on 06 Aug 2026.

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