[Sepsis 2026: diagnosis and treatment].

Authors

Matthias Kochanek, Jan-Hendrik Naendrup

Published in

Medizinische Klinik, Intensivmedizin und Notfallmedizin. Aug 06, 2026. Epub Aug 06, 2026.

Abstract

Sepsis and septic shock require a standardized, time-critical approach: screening of acutely ill high-risk patients, prompt assessment of infection and sepsis-associated organ dysfunction, rapid initiation of appropriate intravenous antimicrobials, and early hemodynamic stabilization. Key elements include obtaining blood cultures before antimicrobials, balanced crystalloids as first-line fluids, norepinephrine as the main vasopressor, and-if vasopressor requirements persist-adjunctive strategies such as vasopressin or hydrocortisone ± fludrocortisone depending on the clinical scenario. Prevention (infection prevention, antibiotic stewardship (ABS)/antimicrobial stewardship (AMS) programs) and structured follow-up aim to reduce long-term sequelae after sepsis.

PMID:
42560494
Bibliographic data and abstract were imported from PubMed on 06 Aug 2026.

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