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Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.

Created on 07 Aug 2026

Authors

Xia Gong, Ying Zheng, Xuyin Ding, Jie Gao, Bolang Cheng, Xinyi Shao, Jian Li, Lelun Jiang, Hossam Haick, Jian Yang

Published in

Nano-micro letters. Volume 19. Issue 1. Aug 07, 2026. Epub Aug 07, 2026.

Abstract

Wearable electronics are rapidly transforming healthcare by enabling continuous, real-time monitoring of physiological and molecular signals directly at the point of need. This shift supports a transition from episodic, generalized care toward precision diagnosis, where individualized, longitudinal data guide early detection, risk stratification, and treatment decisions. Central to this transformation is the convergence of advanced manufacturing and heterogeneous integration strategies, which enable the development of compact, multimodal, and highly conformable diagnostic platforms. In this review, we examine how advances in materials engineering, micro/nanofabrication, and system integration have transformed wearable devices from single-parameter sensors into fully integrated, multimodal diagnostic systems. We outline key architectures and transduction mechanisms and highlight manufacturing approaches such as printing, 3D fabrication, photolithography, and laser writing. We emphasize heterogeneous integration strategies that combine sensing, electronics, power, and communication into skin-conformal platforms for long-term use. These advances enable precision diagnostics through continuous monitoring, multimodal data fusion, and individualized baselines. We also outline key challenges to clinical translation and discuss future directions toward robust, scalable, and clinically actionable systems, providing a strategic outlook for next-generation wearable electronics in precision diagnosis.

PMID:
42566082
Bibliographic data and abstract were imported from PubMed on 07 Aug 2026.

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