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[Physical activity and exercise as medicine; insight into the dose-response relationship].

Created on 07 Aug 2026

Authors

Sabine Schootemeijer, Esmée A Bakker, Thijs M H Eijsvogels

Published in

Nederlands tijdschrift voor geneeskunde. Volume 170. Jul 21, 2026. Epub Jul 21, 2026.

Abstract

Regular engagement in physical activity reduces the risk for chronic diseases and mortality. Nevertheless, more than half of the Dutch population does not adhere to contemporary physical activity guidelines. We provide insight into the dose-response relationship between physical activity and health benefits, and present novel approaches to enhance the uptake of a physically active lifestyle. Important take-aways are as follows: 1) Due to the curvilinear association, risk reductions with increases in physical activity volumes strongly depend on baseline activity levels. 2) High intensity activities produce similar health benefits in relatively less time compared to activities atmoderate- or low intensity. 3) Novel metrics, such as daily steps or exercise snacks expand the physical activity toolbox and could allow more personalized activity prescriptions.

PMID:
42565297
Bibliographic data and abstract were imported from PubMed on 07 Aug 2026.

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