Beyond axial length: posterior segment curvature determining vitreoretinal traction.

Authors

João Heitor Marques, Ana Sofia Martins, Pedro Baptista, Bernardete Pessoa, João Melo Beirão

Published in

Retina (Philadelphia, Pa.). Aug 07, 2026. Epub Aug 07, 2026.

Abstract

To create an algorithm to calculate the posterior radius of curvature of Bruch´s membrane (rBM) on regular optical coherence tomography (OCT) and determine the association between posterior segment shape and vitreoretinal disease.
Retrospective cross-sectional study that included patients with macular hole (MH) or rhegmatogenous retinal detachment (RRD). RRD eyes were matched with MH eyes based on age and axial length (AL), resulting in a final analysis of 43 eyes in each group. OCT B-scans were processed using a custom but open algorithm to calculate the rBM.
rBM was significantly higher in the RRD group (mean 56.1 mm, 95%CI 46.2 - 66.1 mm) whereas the MH group exhibited a steeper curvature (mean 41.6 mm, 95%CI 37.4 - 45.9 mm). No relationship was observed between AL and rBM. Multivariate logistic regression confirmed the independent effect of rBM.
The geometry of the posterior segment differs substantially, independently of AL and age. A rounder posterior segment is associated with RRD, while a steeper curvature is associated with MH, suggesting that globe shape dictates whether vitreoretinal traction manifests peripherally or centrally. rBM on OCT is a simple and reproducible measure that may serve as a risk factor for vitreoretinal disease.

PMID:
42566764
Bibliographic data and abstract were imported from PubMed on 08 Aug 2026.

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