[Time is tissue-deep neck infections and oropharyngeal abscesses].

Authors

Stefan Alexander Rudhart, Alexander Philippe Maas

Published in

HNO. Aug 07, 2026. Epub Aug 07, 2026.

Abstract

Deep neck infections are potentially life-threatening conditions that can spread rapidly due to the complex anatomy of the cervical fascial spaces. They most commonly originate from infections of the upper aerodigestive tract or odontogenic sources and remain associated with significant morbidity and mortality despite advances in treatment.
The aim of this study is to outline the pathophysiology, diagnosis, and management of deep neck infections, emphasizing the importance of timely intervention in accordance with the principle of "time is tissue."
This work is a narrative review based on current literature and clinical guidelines. It addresses anatomical considerations, clinical presentation, imaging modalities, and therapeutic approaches.
Contrast-enhanced CT is the diagnostic gold standard for evaluating disease extent and complications. Deep neck infections are typically polymicrobial. Early intravenous antibiotic therapy and surgical drainage in cases of abscess formation are essential. Airway management plays a central role.
The anatomical structure facilitates rapid spread, potentially reaching the mediastinum. Risk factors such as diabetes and immunosuppression are associated with worse outcomes. Early guideline-based interdisciplinary management is crucial to reduce complications and mortality.

PMID:
42567934
Bibliographic data and abstract were imported from PubMed on 08 Aug 2026.

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