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The Heterogeneity of Long-Term Cardiopulmonary Outcomes in Children Born Preterm May Benefit from Pulmonary Hypertension-Specialty Outpatient Follow-Up.

Created on 08 Aug 2026

Authors

Meaghan C Rousset, Rachel T Sullivan, Anna M Brown, Samantha R Eagle, Eric D Austin

Published in

Pulmonary circulation. Volume 16. Issue 3. Pages e70380. Epub Aug 07, 2026.

Abstract

Preterm birth survivors reaching adulthood are a growing population, with bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, common among this cohort. Infants with BPD are at increased risk for pulmonary vascular disease (PVD) including the development of pulmonary hypertension (PH). We present three preterm patients with a history of BPD-associated PH (BPD-PH) with monitoring throughout their childhood and young adulthood, highlighting the variation in management and late outcomes of each patient. Resolution of PH is reported on transthoracic echocardiogram (TTE) in all patients early in their life. Long-term follow-up was discontinued for one patient, while long-term monitoring in the other two individuals showed evidence of cardiopulmonary complications requiring PH-specialty management. The burden of cardiopulmonary disease associated with prematurity exists beyond early childhood and further research on the long-term management of this population is necessary to mitigate complications.

PMID:
42569060
Bibliographic data and abstract were imported from PubMed on 08 Aug 2026.

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