Clinical and psychosocial correlates of virological severity in paediatric HIV: a retrospective cross-sectional record review in South Africa.

Authors

Kayode Omotayo Akingba, Erhabor Sunday Idemudia, Lawrence E Ugwu

Published in

AIDS care. Pages 1-10. Aug 10, 2026. Epub Aug 10, 2026.

Abstract

This retrospective record review examined psychosocial and clinical correlates of virological severity among children and adolescents aged 0-19 years with detectable viral load in the Ngaka Modiri Molema District, South Africa. Of 124 records screened, 109 were eligible and had a classifiable viral-load outcome. The most robust finding was that reported missed doses were inversely associated with high-level virological failure, whereas ART duration was not independently associated with severity. These findings suggest that routine adherence documentation may reflect not only medication-taking behaviour but also the psychosocial and clinical context in which treatment difficulties are reported.

PMID:
42574479
Bibliographic data and abstract were imported from PubMed on 11 Aug 2026.

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