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Hybrid endoscopic submucosal dissection-endoscopic mucosal resection of large polyps at the ileocecal valve.

Created on 11 Aug 2026

Authors

Taylor Bowler, Rahul Karna, Abubaker Abdalla, Nabeel Azeem

Published in

VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy. Volume 11. Issue 8. Pages 363-367. Epub Apr 27, 2026.

Abstract

Endoscopic resection of polyps at the ileocecal valve (ICV) remains challenging. Herein, we present a review of the current literature and a case series with video of hybrid endoscopic submucosal dissection-endoscopic mucosal resection (ESD-EMR) for the management of polyps at the ICV.
This article and accompanying video outline the technique of hybrid ESD-EMR. This technique was ultimately used for the management of ICV polyps in 10 patients at a single-center institution.
As outlined in the video, endoscopic submucosal dissection was first performed to create a "trench" for the snare to anchor into the lesion and ensure negative margins at the ileal aspect of the lesion. Endoscopic mucosal resection was then performed in a piecemeal or en bloc fashion to complete resection of the polyp. Technical success of the procedure was 100%. Adverse events were noted in 20% of cases, consisting of 1 case of postpolypectomy syndrome (American Society for Gastrointestinal Endoscopy [ASGE] grade I) and 1 case of early bleeding (ASGE grade IIIa). One patient had residual disease on follow-up that was easily managed endoscopically. No patients required surgical referral after endoscopic resection.
We conclude that hybrid ESD-EMR may be an effective resection strategy for the management of large polyps at the ICV.

PMID:
42577245
Bibliographic data and abstract were imported from PubMed on 11 Aug 2026.

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