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Research progress on flavonoid-mediated communication between plants and rhizosphere microorganisms.

Created on 11 Aug 2026

Authors

Yongze Huang, Yunshu Wu, Baiyan Cai

Published in

Archives of microbiology. Volume 208. Issue 11. Aug 11, 2026. Epub Aug 11, 2026.

Abstract

Flavonoids are important components of plant root exudates and key chemical signals mediating cross-kingdom interactions between plants and rhizosphere microorganisms. Based on the theory of chemical communication in the plant rhizosphere, this article systematically reviews the biosynthesis and secretion characteristics of flavonoids, as well as their major regulatory roles in plant-microbe interactions, including symbiotic signal induction in legume-rhizobium associations, arbuscular mycorrhizal fungal colonization, recruitment of plant growth-promoting rhizobacteria, inhibition of pathogenic microorganisms, and interference with quorum sensing. In addition, flavonoids are also involved in host nutrient acquisition and stress-response regulation, affecting the uptake of mineral elements such as phosphorus and iron, as well as plant adaptation to biotic and abiotic stresses. Although significant progress has been made in related research, current evidence remains largely confined to legume model systems. Systematic understanding is still lacking regarding receptor recognition, spatiotemporal dynamic regulation, and field ecological functions of flavonoid signals in non-leguminous staple crops. Future studies should integrate multi-omics analyses, in situ imaging, and functional gene validation to further elucidate the general principles and ecological specificity of flavonoid-mediated rhizosphere interactions. This article aims to provide a theoretical basis for elucidating the mechanisms underlying flavonoid-mediated plant-rhizosphere microbial interactions, advancing the precise regulation of the rhizosphere microecology, and supporting the development of sustainable agriculture.

PMID:
42579146
Bibliographic data and abstract were imported from PubMed on 11 Aug 2026.

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