Authors
Jianguo Dong, Yihan Zhao, Jingwen Zhao, Mengxin Zhao, Xiaoyan He, Weidan Na, Zhao Li, Lin Tian
Published in
Chemical communications (Cambridge, England). Aug 12, 2026. Epub Aug 12, 2026.
Abstract
Realizing precise and sensitive detection of biomarkers is crucial for clinical diagnosis, environmental monitoring, and food safety regulation; however, their performance strongly relies on the properties of sensing materials. As a new type of biological sensing material, Prussian blue analogues (PBAs) have significant advantages, such as a three-dimensional (3D) porous lattice structure for ion transport, tunable multi-nanomicrobial enzyme catalytic properties, excellent electronic conductivity, and reversible redox characteristics. Recent years have witnessed the rapid development of sensors based on PBA-based sensing materials. To gain a better understanding of this interesting field, this review summarizes recent achievements using PBA-based materials for sensing. The review focuses on the structural and chemical composition, physiochemical properties, preparation, and modification of typical PBA-based materials. In addition, the review places special emphasis on the applications of various PBA-based materials in electrochemical, electrochemiluminescence, chemiluminescence, and colorimetry sensors, aiming to present the current status of PBA-based materials for sensing. Furthermore, the review ends with discussions of current challenges and future perspectives of the modifications of PBA-based biosensors, hoping to guide the construction of more advanced sensors.
PMID:
42581699
Bibliographic data and abstract were imported from PubMed on 12 Aug 2026.
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