Neutrophil-to-lymphocyte ratio and metabolic syndrome in patients with schizophrenia spectrum disorders.

Authors

Sunčica Humačkić, Marko Pavlović, Martina Krešić Ćorić, Ivana Sušac

Published in

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina. Volume 23. Issue 2. Aug 07, 2026. Epub Aug 07, 2026.

Abstract

To investigate the differences in neutrophil-to-lymphocyte ratio (NLR) between patients with schizophrenia spectrum disorders (SSD) and healthy controls, and their association with metabolic syndrome (MS) in SSD patients.
A cross-sectional study was conducted involving 70 SSD patients and 55 healthy controls. NLR was calculated using absolute neutrophil and lymphocyte counts (WBC) after obtaining complete blood counts. MS was diagnosed using ATP III criteria, and SSD patients were divided into two subgroups with and without MS.
Patients with SSD had significantly higher total WBC (p = 0.001), as well as neutrophil counts and NLR (both p 0.05).
The findings suggest that inflammation, as indicated by elevated NLR, is linked to SSD independent of MS.

PMID:
42593002
Bibliographic data and abstract were imported from PubMed on 13 Aug 2026.

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