Authors
Syed Sameer Aga, Muhammad Anwar Khan, Mohammed S Thabet, Nawaf Muteb Alharbi, Waleed Mohammed Aljehani, Abdulazziz Khalid Alhazmi, Mohammed Fayih Alotaibi, Saniya Nissar
Published in
Journal of family medicine and primary care. Volume 15. Issue 6. Pages 2309-2317. Epub Jul 27, 2026.
Abstract
Pancreatic cancer (PC) is the seventh-leading cause of cancer-related death worldwide. Studies have established a 2-fold risk of PC among individuals with diabetes mellitus (DM). In this study, we aimed to determine the prevalence and biochemical correlates of DM and in PC patients.
The current retrospective cross-sectional study was conducted between 2016 and 2022. The study sample included all patients aged >18 who were admitted after a primary diagnosis of PC at our center. A comprehensive review of the charts was conducted to gather demographic data, including diabetes and ABO Rh blood group (BG).
A total of 186 PC patients were included, 76 (40.9%) of whom were females and 110 (59.1%) were males. DM was found in 120 (64.5%) patients, of whom 125 (67.2%) were diagnosed pre-PC and constituted 72 (60%) males and 48 (40%) females. The most prevalent type of PC was adenocarcinoma (68.6%), with stage IV being 97.8% of the cases. The most common BG among PC patients was type O in 68 (36.6%) patients, followed by type A in 45 (24.2%). Also, 124 (66.7%) were Rh-positive, while 14 (7.5%) were Rh-negative. Serum CA19-9 was the most commonly detected biomarker, present in 27.4% of patients.
The percentage of DM among PC patients was found to be 64.5%, of whom 3.8% were diagnosed after the diagnosis of PC. Blood group O was the most common; however BG type B was associated with a higher risk of DM in (P = 0.028) in PC patients.
PMID:
42592613
Bibliographic data and abstract were imported from PubMed on 13 Aug 2026.
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