Parallel Declines in Human Papillomavirus 6/11-Related Disease Incidences: A National Study of Anogenital Warts and Recurrent Respiratory Papillomatosis in Norway.

Authors

Madleen Orumaa, Ståle Nygård, Joseph Tota, Parag Mahale, Thea Eline Hetland Falkenthal

Published in

Open forum infectious diseases. Volume 13. Issue 8. Pages ofag456. Epub Jul 29, 2026.

Abstract

Anogenital warts and recurrent respiratory papillomatosis are conditions caused by human papillomavirus (HPV) types 6/11 that can be prevented by vaccination. We analyzed Norwegian national registry data (2010-2023) to assess the impact of the 4-valent HPV vaccine introduced in 2009. Anogenital warts incidence among females aged 15-29 decreased significantly from 1120.0 to 280.6 per 100 000 (annual percentage change: -10.3%), paralleling a sharp decline in recurrent respiratory papillomatosis from 3.7 to 0.6 per 100 000 (annual percentage change: -11.3%). These results strongly support vaccination impact in reducing the burden of HPV 6/11-related diseases, suggesting successful interruption of transmission pathways and substantial population-level protection.

PMID:
42591918
Bibliographic data and abstract were imported from PubMed on 13 Aug 2026.

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