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In situ deep-sea surface-enhanced Raman scattering sensor reveals cyanide as a key factor in cold seep nitrogen cycling.

Created on 15 Aug 2026

Authors

Siyu Wang, Tingting Zhao, Wanying He, Fei Li, Zhicheng Wang, Ruhao Pan, Lianfu Li, Shichuan Xi, Zhendong Luan, Zhiyang Zhang, Bowei Li, Lingxin Chen, Xin Zhang

Published in

Science advances. Volume 12. Issue 33. Pages eaef5836. Aug 14, 2026. Epub Aug 14, 2026.

Abstract

Deep-sea hydrothermal vents and cold seeps, typical ecosystems characterized by abundant carbon but limited nitrogen, support thriving microbial activities. The source of nitrogen has long been a key focus in scientific research. Although cultivation experiments have confirmed the presence of diverse nitrogen-fixing microorganisms, direct in situ evidence has been lacking. Therefore, a deep-sea in situ surface-enhanced Raman scattering sensor has been developed. It can adapt to extreme environment (≥350°C and ≥2000-m depth and LOD < 10-7 M) and has excellent deep-sea application potential. Crucially, the sensor achieved the in situ detection of cyanide (-CN) (>5.7 μM) at cold seep, providing direct evidence for an energy-efficient nitrogen fixation pathway in the microbial communities. Concurrently, the gradient detection results indicated that CN was consumed as a microbial "circulating currency." This finding offers critical in situ evidence for understanding the coupling mechanisms of cold seep carbon, nitrogen, and sulfur cycles, marking a substantial breakthrough in deep-sea sensing technology.

PMID:
42600033
Bibliographic data and abstract were imported from PubMed on 15 Aug 2026.

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