Endoscopic submucosal dissection for a large (exceeding 3 cm) exophytic gastric schwannoma with 24-hour intragastric retention: a case report and brief literature review.

Authors

Rong Xie, Weiwei Zhang, YanningI Mao, Yi Qin, Jiaxu Wang, Qi Luo, Linhua Teng, Jiawen Liu

Published in

Frontiers in gastroenterology (Lausanne, Switzerland). Volume 4. Pages 1703551. Epub Jul 31, 2026.

Abstract

The clinical role of endoscopic resection in the treatment of exophytic gastric schwannomas measuring ≥3 cm remains controversial owing to technical difficulties and a paucity of evidence.
A 58-year-old female patient was admitted for treatment after a gastric mass was discovered during routine physical examination. Endoscopic ultrasonography (EUS) revealed a well-demarcated, hypoechoic submucosal tumor measuring 40.9×32.3 mm. The patient subsequently underwent endoscopic submucosal dissection (ESD) under general anesthesia. Histopathological analysis confirmed the diagnosis of gastric schwannoma, with immunohistochemical staining showing strong S-100 protein positivity. The patient had an uneventful recovery with no procedure-related complications, and there has been no evidence of recurrence to date.
While this single-case experience indicates the technical feasibility of ESD for gastric schwannomas >3 cm, larger-scale prospective studies are required to establish its role in clinical practice.

PMID:
42601915
Bibliographic data and abstract were imported from PubMed on 15 Aug 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.