Generation of induced pluripotent stem cell line NTUHi003-A from a patient with premature ovarian insufficiency.

Authors

Yu-An Chen, Chen-Yu Lu, Chia-En Wu, Tzu-Hsin Chen, Huai-En Lu, Hsin-Fu Chen, Chu-Chun Huang

Published in

Stem cell research. Volume 95. Pages 104076. Aug 11, 2026. Epub Aug 11, 2026.

Abstract

Premature ovarian insufficiency (POI) is characterized by impaired ovarian function before 40 years of age and is associated with heterogeneous etiologies. Herein, we established a human induced pluripotent stem cell (hiPSC) line, NTUHi003-A, from the peripheral blood mononuclear cells (PBMCs) of a patient with POI. The generated hiPSC line exhibited a normal 46, XX karyotype and demonstrated confirmed pluripotency. This cell line provides a valuable cellular platform for disease modeling and mechanistic studies of POI.

PMID:
42603520
Bibliographic data and abstract were imported from PubMed on 16 Aug 2026.

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